Yes, it is very safe to visit Xinjiang now. The Uyghur people are some of the most friendly you’ll ever meet. Most visitors feel it is totally safe in the main tourist areas, though there may be an elevated police presence.
1) A short route to Hotian from Kashgar
2) Drive on the southern edge of Taklimakan Desert.
3) Explore Yarkand Kingdom Tombs
4) Visit the famous Edilis silk factory